tki.org.nz
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1. Thomas-Kilmann Conflict Mode Instrument (TKI®) - The Myers …
Link: https://www.themyersbriggs.com/en-US/Products-and-Services/TKI
Description: WEBUnderstanding conflict resolution styles. The Thomas-Kilmann Conflict Mode Instrument (TKI ®) is the world’s best-selling conflict management tool because it helps trainers, managers, and other professionals conduct productive one-on-one and group discussions about conflict. In a recent survey, 79% of customers consider the TKI tool’s ...
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2. Tyrosine Kinase Inhibitors - StatPearls - NCBI Bookshelf
Link: https://www.ncbi.nlm.nih.gov/books/NBK563322/
Description: WEBJul 18, 2023 · Tyrosine kinase inhibitors (TKI) are a group of pharmacologic agents that disrupt the signal transduction pathways of protein kinases by several modes of inhibition. This activity will review the currently available drugs, their mechanism of action, routes of administration, indications, contraindications, and adverse effects.
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3. Tyrosine Kinase inhibitors (TKIs): Uses & Side Effects - Cleveland Clinic
Link: https://my.clevelandclinic.org/health/treatments/24984-tyrosine-kinase-inhibitors
Description: WEBTyrosine kinase inhibitors are targeted therapies for cancer and other conditions. Like all targeted therapies, its major benefit is killing cancer cells without damaging healthy cells. Tyrosine kinase inhibitors may be an alternative …
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4. Everything You Need to Know About Tyrosine Kinase Inhibitors
Link: https://www.verywellhealth.com/tyrosine-kinase-inhibitors-5442999
Description: WEBJul 28, 2022 · Summary. Tyrosine kinase inhibitors (TKIs) are targeted therapy cancer medications. TKIs are used alone or in conjunction with other treatments to treat many cancers, including some types of breast cancer and leukemia. TKIs have been shown to shrink tumors and slow tumor growth.
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5. Tyrosine Kinase Inhibitors | Leukemia Targeted Therapy | LLS
Link: https://www.lls.org/leukemia/chronic-myeloid-leukemia/treatment/tyrosine-kinase-inhibitor-tki-therapy
Description: WEBTyrosine kinase inhibitors (TKIs) are a type of targeted therapy. TKIs come as pills, taken orally. A targeted therapy identifies and attacks specific types of cancer cells while causing less damage to normal cells. In CML, TKIs target the abnormal BCR::ABL1 protein that causes uncontrolled CML cell growth and block its function, causing the ...
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6. Tyrosine kinase inhibitor - Wikipedia
Link: https://en.wikipedia.org/wiki/Tyrosine_kinase_inhibitor
Description: WEBNilotinib is used to treat (CML), a hematological malignancy. A tyrosine kinase inhibitor ( TKI) is a pharmaceutical drug that inhibits tyrosine kinases. Tyrosine kinases are enzymes responsible for the activation of many proteins by signal transduction cascades.
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7. Lifelong TKI therapy: how to manage cardiovascular and other risks
Link: https://ashpublications.org/hematology/article/2021/1/113/482934/Lifelong-TKI-therapy-how-to-manage-cardiovascular
Description: WEBDec 10, 2021 · As has been stated often, the treatment of chronic myeloid leukemia (CML) was and remains revolutionized, with lower-risk small-molecule-specific targeted therapy with oral ABL tyrosine kinase inhibitors (TKIs) as …
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8. Management of egfr tki–induced dermatologic adverse events
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399609/
Description: WEBUse of an egfr tki affects epidermal-derived tissues; effects include impaired keratinocyte growth, migration, and chemokine expression, which leads to inflammatory cell recruitment and cutaneous injury, including symptoms of rash and periungual inflammation.
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9. The TKI Era in Chronic Leukemias - PMC - National Center for
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8709313/
Description: WEBDec 20, 2021 · Tyrosine kinases are proteins involved in physiological cell functions including proliferation, differentiation, and survival. However, the dysregulation of tyrosine kinase pathways occurs in malignancy, including hematological leukemias such as chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL).
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10. Maintenance Tyrosine Kinase Inhibitors Following Allogeneic
Link: https://pubmed.ncbi.nlm.nih.gov/31669399/
Description: WEBGrant support. It remains unknown whether the administration of tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 after allogeneic hematopoietic cell transplantation (HCT) is associated with improved outcomes for patients with chronic myelogenous leukemia (CML). In this registry study, we analyzed clinical outc ….