Description: Insulin induced gene 1, also known as INSIG1, is a protein which in humans is encoded by the INSIG1 gene.. INSIG1 is short for insulin-induced gene 1; it is located on chromosome 7 (7q36). This human gene encodes for a transmembrane protein of 277 amino acids with probably 6 transmembrane domains. It is localized in the endoplasmic reticulum (ER) and seems to be expressed in all tissues ...
Description: inSIG2019 concluded successfully on 17 Nov 2019 at Ecohub, Kolkata. The event was documented through pictures (available here and here), tweets, videos (which will be uploaded shortly) and other social media posts.The inSIG2019 Fellows will join the existing community of fellows who would be expected to participate in the global IG processes as well as within their own communities.
Description: Regulation. Insulin activates the human INSIG2 promoter in a process mediated by phosphorylated SAP1a.. Akt mediates suppression of Insig2a, a liver-specific transcript encoding the SREBP1c inhibitor INSIG2.. MCHR2 has been observed to significantly decrease INSIG2.. Insig2 is upregulated under hypoxic conditions and is associated with the malignant potential of pancreatic cancer.
Description: Events are generally held at ANMF House, 535 Elizabeth St, Melbourne INSIG hold periodic events such as their End of Year Xmas events, the always popular Biennial Conferences and other specific events..
Description: This gene encodes an endoplasmic reticulum membrane protein that regulates cholesterol metabolism, lipogenesis, and glucose homeostasis. The encoded protein has six transmembrane helices which contain an effector protein binding site. It binds the sterol-sensing domains of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and 3-hydroxy-3-methylglutaryl ...
9. INSIG - What does INSIG stand for? The Free Dictionary
Description: Six weeks after the drug treatment of the Apo[E.sup.-/-] mice fed with a high-fat diet, the mRNA expressions of Insig, PAQR3, SCAP, and SREBP in the aorta, liver, and adipose tissue of the TMP group mice were significantly decreased as compared to the control group (P < 0.01), with no significant difference between the two drug-treatment groups (P > 0.05) (Figure 4).
10. INSIG - Immunisation Nurse Special Interest Group