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1. FDA approves label changes for antimalarial drug …
fda.gov
Link: https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-approves-label-changes-antimalarial-drug-mefloquine-hydrochloride
Description: WEBThe U.S. Food and Drug Administration (FDA) is advising the public about strengthened and updated warnings regarding neurologic and psychiatric side effects associated with …
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2. Mefloquine - Assessment of Long-Term Health Effects of …
nih.gov
Link: https://www.ncbi.nlm.nih.gov/books/NBK556592/
Description: WEBFeb 25, 2020 · Also in 2011, FDA reviewed available data for mefloquine use during pregnancy and reclassified it from category C (animal reproduction studies have shown … Published: 2020/02/25
Published: 2020/02/25 -
3. Mefloquine
microsoft.com
Link: https://go.microsoft.com/fwlink/?linkid=2100071&clcid=0x409
Description: Common brand names: LariamOVERVIEWSIDE EFFECTSINTERACTIONSDOSAGEInteractionsInteractionsBefore taking this medication, tell your doctor if you've had:Mental/mood disorders (such as depression, anxiety, schizophrenia)SeizuresHeart problemsLiver disorder Mental/mood disorders (such as depression, anxiety, schizophrenia) Seizures Heart problems Liver disorder Artemether-lumefantrine Beta-blockers (such as atenolol, propranolol) Chloroquine Halofantrine Ketoconazole Quinidine Quinine Drugs for seizures (such as phenytoin, valproic acid) Ziprasidone May cause dizziness ; Medication should be taken with plenty of water. ; Take with food. ; Call your doctor immediately if you have mental/mood changes like confusion, new/worsening feelings of sadness/fear, thoughts of suicide, or unusual behavior. ; This drug may impair the ability to operate a vehicle, vessel (e.g., boat), or machinery. Use care until you become familiar with its effects. ;
Mental/mood disorders (such as depression, anxiety, schizophrenia)SeizuresHeart problemsLiver disorderArtemether-lumefantrineBeta-blockers (such as atenolol, propranolol)ChloroquineHalofantrineKetoconazoleQuinidineQuinineDrugs for seizures (such as phenytoin, valproic acid)ZiprasidoneMay cause dizziness ; Medication should be taken with plenty of water. ; Take with food. ; Call your doctor immediately if you have mental/mood changes like confusion, new/worsening feelings of sadness/fear, thoughts of suicide, or unusual behavior. ; This drug may impair the ability to operate a vehicle, vessel (e.g., boat), or machinery. Use care until you become familiar with its effects. ; -
4. CDC - Malaria - Features - FDA Revises Mefloquine Labeling
cdc.gov
Link: https://www.cdc.gov/malaria/features/mefloquinelabeling.html
Description:
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5. Mefloquine - Wikipedia
wikipedia.org
Link: https://en.wikipedia.org/wiki/Mefloquine
Description: OverviewHistoryMedical usesAdverse effectsContraindicationsPregnancy and breastfeedingPharmacologyResearchMefloquine was formulated at Walter Reed Army Institute of Research (WRAIR) in the 1970s shortly after the end of the Vietnam war. Mefloquine was number 142,490 of a total of 250,000 antimalarial compounds screened during the study. Mefloquine was the first Public-Private Venture (PPV) between the US Department of Defense and a pharmaceutical company. WRAIR transferred all its phase I and phase II clinical trial dat… Pregnancy category: AU: B3 Formula: C₁₇H₁₆F₆N₂O Trade names: Lariam, Mephaquin, Mefliam, others
Pregnancy category: AU: B3Formula: C₁₇H₁₆F₆N₂OTrade names: Lariam, Mephaquin, Mefliam, others -
6. Mefloquine (Lariam®) - Public Health
va.gov
Link: https://www.publichealth.va.gov/exposures/mefloquine-lariam.asp
Description: WEBOct 12, 2023 · Mefloquine was approved by the Food and Drug Administration (FDA) in May 1989. In 2013, the FDA published a safety alert on mefloquine and added a black …
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7. FDA Revises Mefloquine Labeling; Drug Still …
cdc.gov
Link: https://www.cdc.gov/malaria/features/mefloquinelabeling.html
Description: WEBOct 28, 2020 · However, FDA still approves of mefloquine for the prevention and treatment of malaria. Mefloquine is a very effective drug that is well tolerated by most people who …
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8. Absorption - Food and Drug Administration
fda.gov
Link: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/019591s026s028lbl.pdf
Description: WEBMefloquine hydrochloride is a 4-quinolinemethanol derivative with the specific chemical name of (R*, S*)-(±)-α-2-piperidinyl-2,8-bis (trifluoromethyl)-4-quinolinemethanol …
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9. Mefloquine as a prophylaxis for malaria needs to be …
nih.gov
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342532/
Description: WEBJun 24, 2021 · Prior to prescribing mefloquine for prophylaxis, absolute and relative contraindications are taken into consideration (HA Policy 2015). On the other hand, as …