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1. Jaffe reaction - Wikipedia
wikipedia.org
Link: https://en.wikipedia.org/wiki/Jaffe_reaction
Description: WebJaffe reaction of creatinine and picric acid —the oldest clinical methodology still in use. Scientific career. Fields. Biochemistry, Pathology, Pharmacology. Institutions. University of Königsberg. The Jaffe reaction is a colorimetric method used in clinical chemistry to determine creatinine levels in blood and urine.
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2. Creatinine determination according to Jaffe—what does it stand for?
nih.gov
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421578/
Description: WebJan 27, 2011 · In 1886, Max Jaffe discovered a reaction of creatinine with picric acid in an alkaline environment. Although the manuscript describes the nature of a precipitate and does not deal with an analytical assay, Jaffe's landmark paper elucidated the basic principles of the creatinine determination method (originally developed by Otto Folin), …
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3. 2.14: Serum Creatinine (Jaffe Method) - Medicine LibreTexts
libretexts.org
Link: https://med.libretexts.org/Bookshelves/Allied_Health/Book%3A_Clinical_Chemistry_-_Theory_Analysis_Correlation_(Kaplan_and_Pesce)/02%3A_Laboratory_Exercises/2.14%3A_Serum_Creatinine_(Jaffe_Method)
Description: WebCreatinine reacts with picric acid in an alkaline solution to form a reddish colored complex. The reaction is commonly known as the Jaffe reaction and the red colored product as the Janovski complex.
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4. Measurement of creatinine by Jaffe's reaction--determination of
nih.gov
Link: https://pubmed.ncbi.nlm.nih.gov/12635710/
Description: WebAbstract. Creatinine in serum or urine is determined by Jaffe's reaction where creatinine produces quantitatively an orange color with picric acid in alkaline medium. After allowing an incubation time of 15 min at room temperature for color …
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5. Evaluation and comparison of Abbott Jaffe and enzymatic …
nih.gov
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816857/
Description: WebFeb 15, 2017 · Jaffe reaction is the most frequently used creatinine methods in the clinical laboratories, but it is affected by some non‐creatinine chromogens. The other method for routine creatinine analysis is the enzymatic method.
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6. Measurement of Serum Creatinine – Current Status and Future …
nih.gov
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1784008/
Description: WebAbstract. The first methods for the measurement of creatinine in serum and plasma were published over a century ago. Today, the Jaffe reaction using alkaline picrate remains the cornerstone of most current routine methods, after continuous refinements attempting to overcome inherent analytical interferences and limitations.
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7. in this issue - Kidney International
kidney-international.org
Link: https://www.kidney-international.org/article/S0085-2538(23)00079-0/fulltext
Description: WebInterference of urinary albumin-to-creatinine ratio measurement by glycosuria: clinical implications when using SGLT-2 inhibitors. The Jaffe reaction is the most commonly used test to measure creatinine levels. High levels of glucose can interfere with Jaffe, causing it to overestimate creatinine.
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8. To Estimate Creatinine Level in Serum and Urine by Jaffe’s Reaction
springer.com
Link: https://link.springer.com/chapter/10.1007/978-981-10-8186-6_18
Description: WebMar 31, 2018 · To Estimate Creatinine Level in Serum and Urine by Jaffe’s Reaction. Vijay Kumar & Kiran Dip Gill. Chapter. First Online: 31 March 2018. 3332 Accesses. 1 Citations. Abstract. Creatinine is a waste product derived from dehydration of creatine and is …
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9. Trend in creatinine determining methods: Conventional methods …
wiley.com
Link: https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ansa.202000074
Description: WebOct 20, 2020 · The most common method for measuring creatinine levels in serum and urine is based on Jaffe's reaction, in which creatinine changes in alkaline medium and responds with picric acid and turns into orange.
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10. Jaffe vs. Enzymatic Method for Serum Creatinine Measurement
labmedicineblog.com
Link: https://labmedicineblog.com/2017/07/26/jaffe-vs-enzymatic-method-for-serum-creatinine-measurement/
Description: WebJul 26, 2017 · The Jaffe and enzymatic methods are the two most common methods for measuring serum creatinine. The Jaffe method is less expensive than the enzymatic assay ($0.30 vs $2.00 per test based on 2014 list prices) but is more susceptible to interferences.
