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1. Citrate synthase - Wikipedia
Link: https://en.wikipedia.org:443/wiki/Citrate_synthase
Description: WebCitrate synthase is localized within eukaryotic cells in the mitochondrial matrix, but is encoded by nuclear DNA rather than mitochondrial. It is synthesized using cytoplasmic ribosomes, then transported into the mitochondrial matrix. Citrate synthase is commonly used as a quantitative enzyme marker for the presence of intact mitochondria.
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2. Citrate Synthase - an overview | ScienceDirect Topics
Link: https://www.sciencedirect.com:443/topics/biochemistry-genetics-and-molecular-biology/citrate-synthase
Description: WebCitrate synthase (EC 2.3.3.1, formerly 4.1.3.7; (S -)citrate synthase; CS) is the first of a series of eight enzymes involved in the citric acid cycle. The citric acid cycle is also known as the tricarboxylic acid cycle and the Krebs cycle. CS is found in virtually all living cells.
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3. Citrate Synthase Insufficiency Leads to Specific Metabolic …
Link: https://www.ncbi.nlm.nih.gov:443/pmc/articles/PMC9302927/
Description: WebJul 7, 2022 · Citrate Synthase Insufficiency Leads to Specific Metabolic Adaptations in the Heart and Skeletal Muscles Upon Low-Carbohydrate Diet Feeding in Mice - PMC. Journal List. Front Nutr. PMC9302927. As a library, NLM provides access to scientific literature.
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4. Citrate synthase: structure, control, and mechanism - PubMed
Link: https://pubmed.ncbi.nlm.nih.gov:443/3013232/
Description: WebCitrate synthase: structure, control, and mechanism
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5. 26.11 How Do Enzymes Work? Citrate Synthase - OpenStax
Link: https://openstax.org:443/books/organic-chemistry/pages/26-11-how-do-enzymes-work-citrate-synthase
Description: WebCitrate synthase is a globular protein of 433 amino acids with a deep cleft lined by an array of functional groups that can bind to the substrate, oxaloacetate. On binding oxaloacetate, the original cleft closes and another opens up nearby to bind acetyl CoA.
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6. Biochemistry, Citric Acid Cycle - StatPearls - NCBI Bookshelf
Link: https://www.ncbi.nlm.nih.gov:443/books/NBK541072/
Description: WebMay 1, 2023 · Introduction. The citric acid cycle serves as the mitochondrial hub for the final steps in carbon skeleton oxidative catabolism for carbohydrates, amino acids, and fatty acids. Each oxidative step, in turn, reduces a coenzyme such as nicotinamide adenine dinucleotide (NADH) or flavin adenine dinucleotide (FADH2).
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7. Emergence of fractal geometries in the evolution of a ... - Nature
Link: https://www.nature.com:443/articles/s41586-024-07287-2
Description: WebApr 10, 2024 · Citrate synthase from the cyanobacterium Synechococcus elongatus is shown to self-assemble into Sierpiński triangles, a finding that opens up the possibility that other naturally occurring ...
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8. 16.2: Reactions of the Citric Acid Cycle - Biology LibreTexts
Link: https://bio.libretexts.org:443/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/02%3A_Unit_II-_Bioenergetics_and_Metabolism/16%3A_The_Citric_Acid_Cycle/16.02%3A__Reactions_of_the_Citric_Acid_Cycle
Description: WebJul 23, 2023 · It also produces NADH for mitochondrial e- transport/ATP production. Notice that is thermodynamically unfavorable (in the standard state) but the reaction is pulled to citrate formation by the first and next step of the cycle, citrate synthase. The reaction is shown in Figure \(\PageIndex{28}\).
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9. Structure of ATP citrate lyase and the origin of citrate synthase in
Link: https://www.nature.com:443/articles/s41586-019-1095-5
Description: WebApr 3, 2019 · Across different kingdoms of life, ATP citrate lyase (ACLY, also known as ACL) catalyses the ATP-dependent and coenzyme A (CoA)-dependent conversion of citrate, a metabolic product of the Krebs...
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10. Citrate Synthase - an overview | ScienceDirect Topics
Link: https://www.sciencedirect.com:443/topics/pharmacology-toxicology-and-pharmaceutical-science/citrate-synthase
Description: WebCitrate synthase (CS) is a one of the chief enzyme of the TCA cycle, which derives the rate-limiting step of the TCA cycle [818082]. This enzyme has been found in mitochondria and functions to catalyze the synthesis of citrate from acetyl-CoA and oxaloacetate.
