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1. Donating Plasma: What Are the Side Effects? - Healthline
Link: https://www.healthline.com/health/donating-plasma-side-effects
Description: WebNov 9, 2017 · Citrate reaction. Arterial puncture. Tips. Donating plasma can cause common but usually minor side effects like dehydration and fatigue. Serious side effects may occur, but these are rare....
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2. Citrate Reaction After Plasma Donation: How Long to Recover
Link: https://unitedsocietydonations.com/citrate-reaction-after-plasma-donation/
Description: WebApr 16, 2023 · The effects of citrate reaction after plasma donation include the following: Hypocalcemia: Citrate binds to calcium, leading to low calcium levels in the blood. This can result in numbness, muscle cramps, and spasms after plasma donation. Cardiac complications: Citrate can affect the heart’s electrical system.
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3. Severe citrate toxicity complicating volunteer apheresis platelet
Link: https://pubmed.ncbi.nlm.nih.gov/17111419/
Description: WebEmpirical treatment with intravenous calcium gluconate was initiated, and muscle contractions slowly subsided over approximately 10 to 15 minutes. The events are consistent with a severe reaction to calcium chelation by sodium citrate anticoagulant resulting in symptomatic systemic hypocalcemia.
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4. Donating plasma: What are the side effects and risks? - Medical News Today
Link: https://www.medicalnewstoday.com/articles/319162
Description: WebJun 2, 2020 · Citrate reaction. Citrate is a substance added to the blood during plasma donation to prevent clotting. Some people have a reaction to this substance. If this happens, the person may...
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5. The citric acid cycle | Cellular respiration (article) | Khan Academy
Link: https://www.khanacademy.org/science/biology/cellular-respiration-and-fermentation/pyruvate-oxidation-and-the-citric-acid-cycle/a/the-citric-acid-cycle
Description: WebStep 1. In the first step of the citric acid cycle, acetyl CoA joins with a four-carbon molecule, oxaloacetate, releasing the CoA group and forming a six-carbon molecule called citrate. Step 2. In the second step, citrate is converted into its isomer, isocitrate.
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6. Adverse events associated with apheresis procedures: Incidence …
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613659/
Description: WebThe rate of vascular injury (VI), Citrate reaction (CR), and Presyncopal/Syncopal (PS/S) in plateletpheresis was 1.6% (52/3,120), 0.96% (30/3,120), and 0.096% (03/3,120), respectively [Table 3]. The rate of CR in TPE and PBSC was 1.23% (02/162) and 2.3% (02/85), respectively. The rate of PS/S in PBSC was 1.17% (01/85) [Table 4]. AEs for ...
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7. Incidence and severity of adverse events among platelet donors
Link: https://journals.lww.com/md-journal/Fulltext/2020/12240/Incidence_and_severity_of_adverse_events_among.26.aspx
Description: WebJan 1, 2021 · Citrate reactions included numbness, tingling in the lips, paresthesia to the hands, chills, abdominal cramps, muscle cramps, tetany, visual disturbances, loss of consciousness, cardiac arrhythmia, and seizures.
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8. Have Concerns? Check Out These Answers to Common Questions.
Link: https://www.hhs.gov/givingequalsliving/giveplasma/common-concerns
Description: WebSep 27, 2022 · What is a citrate reaction? The machine that separates your plasma from the other blood components uses a substance called citrate to prevent clotting. Some citrate may enter your bloodstream when giving plasma. Most people experience no side effects from this.
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9. Citrate: How to Get Started and What, When, and How to Monitor?
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231307/
Description: WebOct 9, 2018 · Citrate is the conjugate base of citric acid. It is an intermediate conjugate in the citric acid cycle (Krebs cycle or tricarboxylic acid cycle). After the pyruvate dehydrogenase complex forms acteyl-coenzyme A (acetyl-CoA), citrate synthase catalyzes the condensation of oxaloacetate with acetyl-CoA to form citrate.
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10. Citrate metabolism in blood transfusions and its relationship due …
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483798/
Description: WebApr 15, 2015 · Citrate intoxication is a frequent complication after massive blood transfusions and often presents itself as metabolic alkalosis. The reason this term comes about is due to the conversion of citrate, which is applied as an anticoagulant in blood bags, to bicarbonate, and this conversion happens, predominantly in the liver [ 2 - 4 ].