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1. The citric acid cycle | Cellular respiration (article) | Khan Academy
khanacademy.org
Link: https://www.khanacademy.org/science/biology/cellular-respiration-and-fermentation/pyruvate-oxidation-and-the-citric-acid-cycle/a/the-citric-acid-cycle
Description: WEBThe citric acid cycle is a closed loop; the last part of the pathway reforms the molecule used in the first step. The cycle includes eight major steps. In the first step of the cycle, acetyl CoA combines with a four-carbon acceptor molecule, oxaloacetate, to form a six-carbon molecule called citrate.
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2. Citric acid cycle - Wikipedia
wikipedia.org
Link: https://en.wikipedia.org/wiki/Citric_acid_cycle
Description: WEBThe citric acid cycle begins with the transfer of a two-carbon acetyl group from acetyl-CoA to the four-carbon acceptor compound (oxaloacetate) to form a six-carbon compound (citrate). The citrate then goes through a series of chemical transformations, losing two carboxyl groups as CO 2.
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3. 16.3: Regulation of the Citric Acid Cycle - Biology LibreTexts
libretexts.org
Link: https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/02%3A_Unit_II-_Bioenergetics_and_Metabolism/16%3A_The_Citric_Acid_Cycle/16.03%3A_Regulation_of_the_Citric_Acid_Cycle
Description: WEBJul 21, 2023 · Citrate synthase is regulated in part by the availability of substrate acetyl-CoA and oxaloacetate. It is inhibited by NADH and also citrate, a competitive inhibitor of oxaloacetate binding. Succinyl-CoA, a downstream product of the citric acid cycle, is a competitive inhibitor of acetyl-CoA binding.
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4. Biochemistry, Citric Acid Cycle - StatPearls - NCBI Bookshelf
nih.gov
Link: https://www.ncbi.nlm.nih.gov/books/NBK541072/
Description: WEBMay 1, 2023 · Steps of the Citric Acid Cycle: Citrate synthesis. Citrate synthase catalyzes the condensation reaction of acetyl-CoA and oxaloacetate (the cycle’s final product) to form citrate, initiating the citric acid cycle. Note that this reaction is virtually irreversible with a delta-G-prime of -7.7 Kcal/M (thus strongly favoring citrate formation).
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5. 7.4: The Citric Acid Cycle - Biology LibreTexts
libretexts.org
Link: https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Map%3A_Raven_Biology_12th_Edition/07%3A_How_Cells_Harvest_Energy/7.04%3A_The_Citric_Acid_Cycle
Description: WEBThe eight steps of the cycle are a series of redox, dehydration, hydration, and decarboxylation reactions that produce two carbon dioxide molecules, one GTP/ATP, and reduced forms of NADH and FADH2.
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6. 16.2: Reactions of the Citric Acid Cycle - Biology LibreTexts
libretexts.org
Link: https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/02%3A_Unit_II-_Bioenergetics_and_Metabolism/16%3A_The_Citric_Acid_Cycle/16.02%3A__Reactions_of_the_Citric_Acid_Cycle
Description: WEBJul 23, 2023 · Pyruvate + Oxaloacetate → citrate + CO 2. This is correct but omits the initial conversion of pyruvate to acetyl-CoA. Hence the "end product" of the pathway (oxaloacetate) reforms the beginning reactant (citrate) so …
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7. Pyruvate oxidation | Cellular respiration (article) | Khan Academy
khanacademy.org
Link: https://www.khanacademy.org/science/biology/cellular-respiration-and-fermentation/pyruvate-oxidation-and-the-citric-acid-cycle/a/pyruvate-oxidation
Description: WEBOverall, pyruvate oxidation converts pyruvate—a three-carbon molecule—into acetyl CoA —a two-carbon molecule attached to Coenzyme A—producing an NADH and releasing one carbon dioxide molecule in the process. Acetyl CoA acts as fuel for the citric acid cycle in the next stage of cellular respiration.
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8. Krebs / citric acid cycle (video) | Khan Academy
khanacademy.org
Link: https://www.khanacademy.org/science/biology/cellular-respiration-and-fermentation/pyruvate-oxidation-and-the-citric-acid-cycle/v/krebs-citric-acid-cycle
Description: WEBAbout. Transcript. Overview of the Krebs or citric acid cycle, which is a series of reactions that takes in acetyl CoA and produces carbon dioxide, NADH, FADH2, and ATP or GTP. Created by Sal Khan. Questions. Tips & Thanks. Want to join the conversation? Sort by: Top Voted. crystaljganatra. 13 years ago.
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9. The Citric Acid Cycle and Fatty Acid Biosynthesis
nih.gov
Link: https://www.ncbi.nlm.nih.gov/books/NBK2413/
Description: WEB< Prev Next > Chapter 12 The Citric Acid Cycle and Fatty Acid Biosynthesis. David J. Kelly and Nicky J. Hughes. Author Information and Affiliations. Go to: Diversity and Multiple Roles of the Citric Acid Cycle in Prokaryotes. The citric acid cycle (CAC) is arguably the most important central metabolic pathway in living cells.
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10. Physiology, Krebs Cycle - StatPearls - NCBI Bookshelf
nih.gov
Link: https://www.ncbi.nlm.nih.gov/books/NBK556032/
Description: WEBNov 23, 2022 · Regulation of the TCA cycle occurs at three distinct points that include the three following enzymes: citrate synthase, isocitrate dehydrogenase, and alpha-ketoglutarate dehydrogenase. The cycle also plays a role in replenishing precursors for the storage form of fuels such as amino acids and cholesterol.[1]
